Protective links between vitamin D, inflammatory bowel disease and colon cancer

girl in sun and sunflowersArticle Written by Stacey Meeker, Audrey Seamons, Lillian Maggio-Price, and Jisun Paik
World Journal of Gastroenterology (2016); 22(3):933-948
January 21, 2016

Abstract

Vitamin D deficiency has been associated with a wide range of diseases and multiple forms of cancer including breast, colon, and prostate cancers. Relatively recent work has demonstrated vitamin D to be critical in immune function and therefore important in inflammatory diseases such as inflammatory bowel disease (IBD). Because vitamin D deficiency or insufficiency is increasingly prevalent around the world, with an estimated 30%-50% of children and adults at risk for vitamin D deficiency worldwide, it could have a significant impact on IBD. Epidemiologic studies suggest that low serum vitamin D levels are a risk factor for IBD and colon cancer, and vitamin D supplementation is associated with decreased colitis disease activity and/or alleviated symptoms. Patients diagnosed with IBD have a higher incidence of colorectal cancer than the general population, which supports the notion that inflammation plays a key role in cancer development and underscores the importance of understanding how vitamin D influences inflammation and its cancer-promoting effects. In addition to human epidemiological data, studies utilizing mouse models of colitis have shown that vitamin D is beneficial in preventing or ameliorating inflammation and clinical disease. The precise role of vitamin D on colitis is unknown; however, vitamin D regulates immune cell trafficking and differentiation, gut barrier function and antimicrobial peptide synthesis, all of which may be protective from IBD and colon cancer. Here we focus on effects of vitamin D on inflammation and inflammation-associated colon cancer and discuss the potential use of vitamin D for protection and treatment of IBD and colon cancer.

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Gut Immune Cells Cut Inflammation in Multiple Sclerosis

cellsArticle Written by Nicholas Weiler and Jim Oldfield
January 3, 2019
University of California San Francisco (UCSF)
www.ucsf.edu

Researchers at the University of Toronto and UC San Francisco have discovered that the intestine is the source of immune cells that reduce brain inflammation in people with multiple sclerosis (MS), and that increasing the number of these cells blocks inflammation entirely in a preclinical model of the disease.

The cells in question are plasma cells – white blood cells that originate as B cells in the bone marrow but change their behavior when triggered by microbes in the gut. Studying mice and samples from human MS patients, the researchers found that plasma cells that reside in the gut and produce Immunoglobulin A (IgA) antibodies appear to migrate to the central nervous system and produce an anti-inflammatory effect during MS flare-ups.

MS is an autoimmune disease, driven by other types of immune cells (including B and T cells) that attack myelin, the protective coating that surrounds nerve fibers. Recent clinical studies have shown drugs that target B cells mitigate MS, while those that target plasma cells make the disease worse. The current study offers an explanation for these divergent results.

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Improving communication skills in children With allergy-related autism Using nambudripad’s allergy elimination Techniques: a Pilot study

children readingArticle Written by Jacob Teitelbaum, MD; Devi S. Nambudripad, MD, PhD, DC, LAc; Yvonne Tyson, MD; Ming Chen, MD; Robert Prince, MD; Mala M. Moosad, RN, LAc, PhD; Laurie Teitelbaum, MS;  Integrative Medicine vol 10, No. 5; October 1, 2011
naet.com

ABSTRACT

Background: Autism prevalence increased more than 50% between 2002 and 2006. We hypothesized that major contributors to the development and symptoms of autism include food and nutrient sensitivities. Desensitization to multiple allergens forms the basis of the Nambudripad Allergy Elimination Techniques (NAET) treatment for autism.

Subjects and Intervention: Sixty children (2.5-10 years old) with autism were randomly assigned to treatment or control groups. The treatment group (26 boys and four girls) received NAET treatments (combining acupressure and kinesiology) for 50 key allergens for 1 year. The nonblinded control group (25 boys and five girls) did not receive any NAET treatments. Each group was allowed to continue with any other therapies they had been receiving. Neuromuscular Sensitivity Testing (NST, kinesiology and muscle testing) was used to determine which substances triggered sensitivity reactions in each child, and NAET acupressure treatments were then used to elimi- nate the sensitivities.

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Blood Type Diet Test Kits

bloodArticle Written by D'Adamo Personalized Nutrition
February 16, 2019
4yourtype.com

Don't know your blood type?

Are you ready to begin the journey into GenoType? Get the information you need, with our easy to use home testing kits. Each kit has been specially designed by Dr. Peter D'Adamo and contains all the tools you'll need to quickly and easily determine your blood type, GenoType, or secretor status - all without trips to the doctor, waiting days for test results, or expensive lab fees.

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Crohn’s Disease Diet & Natural Treatment Plan

glitter medicineArticle Written by Annie Price, CHHC February 16, 2016
Dr. Axe.com

Have you been suffering from excessive diarrhea and abdominal pain on a regular basis? You might have Crohn’s disease. However, there’s good news. You can treat this condition naturally with a Crohn’s disease diet, along with making other lifestyle changes.

What is Crohn’s disease, exactly? This inflammatory bowel disease (IBD) causes inflammation of the lining of your digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. It’s estimated that 1.4 million Americans suffer from Crohn’s disease or ulcerative colitis (collectively known as inflammatory bowel diseases or IBD). (1)

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Effective Treatment of Chronic Fatigue Syndrome and Fibromyalgia

cfs studyArticle Written by Jacob E. Teitelbaum, MD, Barbara Bird, M.T.,C.L.S, Robert M. Greenfield, MD1, Alan Weiss, MD1, Larry Muenz, Ph.D2, Laurie Gould, BS
Journal of Chronic Fatigue Syndrome Vol. 8, No. 2, 2001. PP3-28 www.endfatigue.com

A Randomized, Double-Blind, Placebo- Controlled, Intent to Treat Study

Abstract

Background

Hypothalamic dysfunction has been suggested in Fibromyalgia (FMS) and Chronic Fatigue Syndrome (CFS). This dysfunction may result in disordered sleep, subclinical hormonal deficiencies, and immunologic changes. Our previously published open trial showed that patients usually improve by using a protocol which treats all the above processes simultaneously. The current study examines this protocol using a randomized, double-blind design with an intent-to-treat analysis.

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Low-Dose Immunotherapy (LDI)

immune systemArticle Written by Ty Vincent, MD  Townsend Letter June 1, 2017
www.townsendletter.com

Low-dose immunotherapy is an expanded application of LDA (low-dose allergy therapy), treatment made available to practitioners in the US by W. A. Shrader, MD, for the resolution of allergies and select autoimmune disorders. An earlier version of that technique, EPD (enzyme-potentiated desensitization), has been used in the field of integrative medicine since it was developed in the 1960s by Leonard McEwen, MD, an allergist in the UK. These techniques have been applied very successfully in the treatment of more than 60 indications, primarily allergy, asthma, and chemical sensitivities; autoimmune disorders including rheumatoid arthritis, systemic lupus, and ankylosing spondylitis; and other select immune-mediated conditions.

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